1 Synthesis and characterization of the autoregulatory domain of PFKFB3 H. Macut, S. Pellegrino, M.L. Gelmi International Symposium on Medicinal Chemistry : book of abstracts Green http://hdl.handle.net/2434/489548 http://hdl.handle.net/2434/489548 2 Design, synthesis and in vitro evaluation of modulators of PFKFB3 autoregulatory domain MACUT, HELENA; HU, XIAO; GELMI, MARIA LUISA; PELLEGRINO, SARA; TARANTINO, DELIA 10th Joint Meeting on medicinal chemistry, 25.-28.6.2017 Dubrovnik, Croatia. Green http://hdl.handle.net/2434/516356 http://hdl.handle.net/2434/516356 3 Novel MMP-inhibiting peptides for stabilizing atherosclerotic plaques" "ABDALI, ANAHITA, MACUT, HELENA PELLEGRINO, SARA, GELMI, MARIA LUISA, BELLOSTA, STEFANO " 85th European Atherosclerosis Society (EAS) Congress in Prague: Science at a Glance Green http://hdl.handle.net/2434/508315 http://hdl.handle.net/2434/508315 4 "Combining 3D-RISM with hydrophatic characteristic water evaluation: first step preparation for further PLANTS virtual screening with flexible explicit water molecules HU, XIAO CONTINI, ALESSANDRO " 12th German Conference on Chemoinformatics Green http://hdl.handle.net/2434/517787 http://hdl.handle.net/2434/517787 5 Combining 3D-RISM with hydropathic charateristic water evaluation: first step preparation for further PLANTS virtual screening with flexible explicit water molecules HU, XIAO, CONTINI, ALESSANDRO " eCheminfo workshop in Drug Design Green http://hdl.handle.net/2434/516738 http://hdl.handle.net/2434/516738 6 DESIGN, SYNTHESIS AND IN VITRO EVALUATION OF PFKFB3 PHOSPHATASE ACTIVITY ALLOSTERIC MODULATORS "Helena Macut DISFARM - Section of General and Organic Chemistry ""A. Marchesini"", University of Milan, Via Venezian 21, 20133 Milan, Italy. ; Xiao Hu; Delia Tarantino; Luca Giovanni Regazzoni; Ettore Gilardoni; Sara Pellegrino; Maria Luisa Gelmi" International Symposium on Medicinal Chemistry Lublijana No 10.5281/zenodo.1415341 7 Annual Research Day: Project summary for Elevator Pitch Smolders, Valérie F. 'Kaag dag : Annual Research meeting Leiden, Green 10.5281/zenodo.1402470 https://figshare.com/articles/Annual_Research_Day_Project_summary_for_Elevator_Pitch/7007132 8 Inflammation in Vein Graft Disease Margreet R. de Vries, Paul H. A. Quax Frontiers in Cardiovascular Medicine Green 10.3389/fcvm.2018.00003 http://europepmc.org/articles/PMC5787541 9 Plaque angiogenesis and intraplaque hemorrhage in atherosclerosis Laura Parma, Fabiana Baganha, Paul H.A. Quax, Margreet R. de Vries European Journal of Pharmacology Green 10.1016/j.ejphar.2017.04.028 https://zenodo.org/record/825907 10 An Efficient Implementation of the Nwat-MMGBSA Method to Rescore Docking Results in Medium-Throughput Virtual Screenings Irene Maffucci, Xiao Hu, Valentina Fumagalli, Alessandro Contini Frontiers in Chemistry Gold 10.3389/fchem.2018.00043 https://figshare.com/articles/An_Efficient_Implementation_of_the_Nwat-MMGBSA_Method_to_Rescore_Docking_Results_in_Medium-Throughput_Virtual_Screenings/5387575 11 Plaque angiogenesis and its relation to inflammation and atherosclerotic plaque destabilization Margreet R. de Vries, Paul H.A. Quax Current Opinion in Lipidology Green doi: 10.1097/MOL.0000000000000339 12 Novel MMP-inhibiting peptides for stabilizing atherosclerotic plaques Anahita Abdali, Helena Macut, Xiao Hu, Sara Pellegrino, Alberto Corsini, Maria Luisa Gelmi, Stefano Bellosta Atherosclerosis Green 10.1016/j.atherosclerosis.2017.06.162 http://hdl.handle.net/2434/508315 13 Synthesis of PFKFB3 inhibitors for Positron Emission Tomography imaging of atherosclerotic plaque Carlo, De Dominicis Graduate School 2017 Winter Symposium at the University of Aberdeen Green 10.5281/zenodo.827185 https://figshare.com/articles/Synthesis_of_PFKFB3_inhibitors_for_Positron_Emission_Tomography_imaging_of_atherosclerotic_plaque/6493210 14 Animal models of atherosclerosis Besa Emini Veseli, Paola Perrotta, Gregory R.A. De Meyer, Lynn Roth, Carole Van der Donckt, Wim Martinet, Guido R.Y. De Meyer European Journal of Pharmacology Gold 10.1016/J.EJPHAR.2017.05.010 http://hdl.handle.net/10067/1428740151162165141 15 [18F]AZ68: a PFKFB3 targeted PET tracer for imaging atherosclerotic plaque De Dominicis, C. Dall'Angelo Sergio; Perrotta Paola; Zanda Matteo; Staelens Steven; De Meyer Guido; Wyffels Leonie Green http://doi.org/10.5281/zenodo.1422742 16 The epigenetic factor PCAF regulates vascular inflammation and is essential for intimal hyperplasia development Rob C. M. de Jong, Mark M. Ewing, Margreet R. de Vries, Jacco C. Karper, Antonius J. N. M. Bastiaansen, Hendrika A. B. Peters, Fabiana Baghana, Peter J. van den Elsen, Céline Gongora, J. Wouter Jukema, Paul H. A. Quax PLOS ONE Green 10.1371/journal.pone.0185820 17 Blockade of vascular endothelial growth factor receptor 2 inhibits intraplaque haemorrhage by normalization of plaque neovessels M. R. de Vries, L. Parma, H. A. B. Peters, A. Schepers, J. F. Hamming, J. W. Jukema, M. J. T. H. Goumans, L. Guo, A. V. Finn, R. Virmani, C. K. Ozaki, P. H. A. Quax Journal of Internal Medicine Green doi: 10.1111/joim.12821 18 Advances in the treatment of explicit water molecules in docking and binding free energy calculations Xiao Hu, Irene Maffucci, Alessandro Contini Current Medicinal Chemistry Green doi: 10.2174/0929867325666180514110824 19 Pharmacological strategies to inhibit intra-plaque angiogenesis in atherosclerosis Paola Perrotta, Besa Emini Veseli, Bieke Van der Veken, Lynn Roth, Wim Martinet, Guido R.Y. De Meyer Vascular Pharmacology Green DOI: 10.1016/j.vph.2018.06.014 20 Differentially Expressed Proteins in Pulmonary Endothelial Cells in Chronic Thromboembolic Pulmonary Hypertension "S.B. Nukala , O. Tura , L. Regazzoni , C. Marinello , A. Abdali , G. Aldini , V.F. Smolders, I. Blanco , J.A. Barbera , M. Cascante , M. Carini " American Journal of Respiratory and Critical Care Medicine 2018; 197:A3738 ATS International conference, Green http://hdl.handle.net/2434/590474 http://hdl.handle.net/2434/590474 21 "Virtual screening approach in drug discovery targeting the PFKFB3 kinase binding site" Cristofori, Virginia; Contini, Alessandro eCheminfo workshop in Drug Design, 18-22 July 2016 University of Milan Green 10.5281/zenodo.826382 22 "Structure-based design and synthesis of new PFKFB3 kinase inhibitors as candidate therapeutics for treating atherosclerosis " " Cristofori, Virginia; Stanzione, Francesca; Zanda, Matteo; Contini, Alessandro, Medicinal Chemistry Residential Summer School Green 10.5281/zenodo.826380 23 "Structure-based design and synthesis of new PFKFB3 kinase inhibitors as candidate therapeutics for treating atherosclerosis " " Cristofori, Virginia " Winter Symposium 16th and 17th of February, Aberdeen University Green 10.5281/zenodo.827178 10.5281/zenodo.827178 24 "Dysfunctional endothelial cells in patients with chronic thromboembolic pulmonary hypertension" Valérie Françoise Smolders; Joan Albert Barberà; Olga Tura-Ceide" ERS 2017 on September 11th 2017, Milan, Italy. Green DOI 10.5281/zenodo.1402475 DOI 10.5281/zenodo.1402475 25 Endothelial cells dysfunctionality associated to acute myocardial infarction: regulation of metabolic pathways as a new therapeutic strategy. Erika Zodda, Anusha Jayaraman, Pedro de Atauri, Ramón Messeguer, Olga Tura-Ceide, Timothy M. Thomson, & Marta Cascante. FEBS3+ Barcelona 2017 Green http://doi.org/10.5281/zenodo.1342535 26 "Derivation and characterization of endothelial cells from patients with chronic thromboembolic pulmonary hypertension" " Valérie Françoise Smolders; Joan Albert Barberà; Olga Tura-Ceide ATS 2018 2018, San Diego (CA), USA. Green 10.5281/zenodo.1402522 10.5281/zenodo.1402522 27 "Metabolic characterization of endothelial cells dysfunctionality associated to acute myocardial infarction" Erika Zodda; Anusha Jayaraman; Pedro de Atauri; Ramon Messeguer; Olga Tura-Ceide; Timothy M. Thomson; Marta Cascante" ENABLE Conference - The 1st European PhD and Postdoc, 15-17 Noviembre 2017, Palau Casades , Barcelona (Spain) Green 10.5281/zenodo.1342612 10.5281/zenodo.1342612 28 Mass Spectrometry-Based Label Free Quantitative Proteomics to study the effect of 3-PO in endothelial cells "NUKALA, SARATH BABU D'AMATO, ALFONSINA, REGAZZONI, LUCA GIOVANNI,ALDINI, GIANCARLO, CARINI, MARINA" Joint Meeting in Medicinal Chemistry MedChemSicily Palermo nel 2018. Green http://hdl.handle.net/2434/590476 http://hdl.handle.net/2434/590476 29 "Vascular Discovery: From Genes to Medicine Scientific " " A. Abdali, A. Corsini, D. Baci, C. De Dominicis, M. Zanda, M.L. Gelmi, S. Bellosta" Vascular Discovery: From Genes to Medicine Scientific Conference S. Francisco Green http://hdl.handle.net/2434/585140 http://hdl.handle.net/2434/585140 30 Angiogenesis inhibition with novel compounds targeting the key glycolytic enzyme PFKFB3 Abdali, A; A. Corsini, D. Baci, C. De Dominicis, M. Zanda, M. L. Gelmi, S. Bellosta. 86th Congress of the European Atherosclerosis Society EAS, Lisbon (Portugal) Green http://hdl.handle.net/2434/585142 http://hdl.handle.net/2434/585142 31 "Novel compounds targeting PFKFB3, the key glycolytic enzyme, as a way to inhibit angiogenesis "Anahita Abdali, Bellosta Stefano, Corsini Alberto, Carlo De Dominicis, Matteo Zanda, Gelmi Maria Luisa " SISA Palermo, 19-21 November 2017 Green http://hdl.handle.net/2434/585138 http://hdl.handle.net/2434/585138 32 “In vitro study on the effects of inhibitors of angiogenesis in atherosclerosis” L. Parma, C. De Dominicis, H. A. B. Peters, M. R. De Vries and P. H. A. Quax ESVS spring meeting in Leiden, May 19-20, 2017. Green 10.5281/zenodo.826048 10.5281/zenodo.826048 33 "In vivo evaluation by optical and PET imaging of IP angiogenesis and validation of PFKFB3 inhibitors in a murine vein graft model"Baganha F., De Vries M. and Quax P. Dutch Heart Foundation Green 10.5281/zenodo.832534 10.5281/zenodo.832534 34 Humanized IgG monoclonal anti-phosphorylcholine reduces vein graft failure Fabiana Baganha; Erna Peters; Margreet de Vries; Knut Pettersson; Paul H.A. Quax ESVS spring meeting 2017 Green 10.5281/zenodo.832549 10.5281/zenodo.832549 35 VEGFR2 blockade reduces intraplaque haemorrhage and enhances plaque stability by augmentation of plaque neovessel maturation" Margreet de Vries; Laura Parma; Erna Peters; Jaap Hamming; Marie-José Goumans; Paul Quax" International Vascular Biology Meeting (IVBM), Boston, Massachusetts, USA, 30 Oct – 03 Nov, 2016 Green 10.5281/zenodo.831473 10.5281/zenodo.831473 36 "Dysfunctional endothelial cells in patients with chronic thromboembolic pulmonary hypertension " Valérie Françoise Smolders; Joan Albert Barberà; Olga Tura-Ceide ERS 2017 Green 10.5281/zenodo.1402475 10.5281/zenodo.1402475 37 “P-140 VEGFR2 blockade in murine atherosclerotic vein grafts enhances plaque stability and reduces intraplaque haemorrhage by enhancement of plaque neovessel maturation” M. de Vries, L. Parma, E. Peters, J. Hamming, M.- J. Goumans, P. Quax Perspectives in Vascular Biology meeting , Frankfurt, Green 10.5281/zenodo.1478810 10.5281/zenodo.1478810 38 “In vitro and in vivo study on the effects of inhibitors of angiogenesis in atherosclerosis” Parma L, M. R. De Vries, P. H. A. Quax PhD course Dutch Heart Foundation, Green 10.5281/zenodo.1478817 10.5281/zenodo.1478817 39 " “Design, synthesis and in vitro evaluation of modulators of PFKFB3 phosphatase activity” " H. Macut, X. Hu, D. Tarantino, L. Parma, S. Pellegrino, M. L. Gelmi Marie Curie Alumni Association General Assembly and Annual Conference, Green 10.5281/zenodo.1478786 10.5281/zenodo.1478786 40 “Derivation and characterization of endothelial cells from patients with chronic thromboembolic pulmonary hypertension” V. Smolders, Olga Tura-Ceide, Jéssica Garcia-Lucio, Lucilla Piccari, Victor I. Peinado, Manel Castella, Joan Albert Barberà . spring meeting in Leiden Green 10.5281/zenodo.826143 10.5281/zenodo.826143 41 “Study of central carbon metabolism of Endothelial Cells in normal and pathological conditions” E. Zodda, A. Jayaraman, P. de Atauri, S. Marin, R. Messeguer, O. Tura-Ceide, T. M Thomson, M. Cascante EMBO conference Green 10.5281/zenodo.826394 10.5281/zenodo.826394 42 " ""Derivation and characterisation of endothelial cells from patients with chronic thromboembolic pulmonary hypertension"" " "V. Smolders, O. Tura-Ceide, J. Garcia-Lucio, L. Piccari, V. I. Peinado, M. Castella, J. A. Barberà. " Jornadas Docencia CIBERES/CIBER-BBN 2016. Green 10.5281/zenodo.826133 10.5281/zenodo.826133 43 “Small molecule mediated inhibition of bFGF reduces in vivo angiogenesis and is a promising candidate to combat intraplaque angiogenesis in atherosclerosis” L. Parma, M.R. De Vries, H.A.B. Peters and P.H.A. Quax ESM-EVBO summer school No 10.5281/zenodo.1478821 10.5281/zenodo.1478821 44 Quantitative Proteomics: Strategies and tools to Probe Biology Nukala SB, , MM Idris, Marina Carini European Molecular Biology Laboratory (EMBL), Green http://hdl.handle.net/2434/517613 http://hdl.handle.net/2434/517613 45 "Targeting glycolysis to inhibit intra-plaque angiogenesis." Perrotta P., M.de Vries, W. Martinet , P. Quax ESVS Meeting_Basic and Translation Research in vascular biology. Green https://zenodo.org/record/1482839#.W-gYWXpKiCQ https://zenodo.org/record/1482839#.W-gYWXpKiCQ 46 Target glycolysis to promote stabilization of advanced atherosclerotic plaques ORAL Paola Perrotta Spring Meeting of the Belgian Society of Physiology and Pharmacology 27/04/2018 Green https://zenodo.org/record/1482853#.W-gYLnpKiCQ https://zenodo.org/record/1482853#.W-gYLnpKiCQ 47 “Flexible Water Docking and Virtual Screening Using PLANTS Combined with Tuned Water Selection criteria” X. Hu, A. Contini 11th Triennial Congress of the World Association of Theoretical and Computational Chemists, Green http://hdl.handle.net/2434/599488 http://hdl.handle.net/2434/599488 48 “Docking and Virtual Screening with Flexible Hydration and Potentials in MM-PBSA rescoring” X. Hu, A. Contini, 13th German Conference on Chemoinformatics Green hdl.handle.net/2434/599533 hdl.handle.net/2434/599533 49 "Automatization of the Nwat-MMGBSA method to rescore docking results in medium-throughput virtual screening applications" Hu X.; Contini, A. Triennial Congress of the World Association of Theoretical and Computational Chemists Green hdl.handle.net/2434/524057 hdl.handle.net/2434/524057 50 " “Difference in Virtual Screening Enrichment Using polar and non-polar interactions of MM-PB/GBSA methods” " "X. Hu, A. Contini" echeminfo Oxford 2018 workshop Green hdl.handle.net/2434/599872 51 “A monoclonal human IgG1 phosphorylcholine antibody reduces vein graft remodelling, angiogenesis and intraplaque haemorrhage” Baganha F., M.R. De Vries, Erna Peters, Knut Pettersson and P.H.A. Quax International Vascular Biology Meeting Green 10.5281/zenodo.1489036 10.5281/zenodo.1489036 52 “A monoclonal human IgG1 phosphorylcholine antibody reduces vein graft remodelling, angiogenesis and intraplaque haemorrhage” F. Baganha, M.R. De Vries, Erna Peters, Knut Pettersson and P.H.A. Quax Frontiers in Cardiovascular Green 10.5281/zenodo.1488964 10.5281/zenodo.1488964 53 " “A monoclonal human IgG1 phosphorylcholine antibody reduces vein graft remodelling, angiogenesis and intraplaque haemorrhage” Baganha F., M.R. De Vries, Erna Peters, Knut Pettersson and P.H.A. Quax RVMM Meeting Green 10.5281/zenodo.1489044 10.5281/zenodo.1489044 54 F“A monoclonal human IgG1 phosphorylcholine antibody reduces vein graft remodelling, angiogenesis and intraplaque haemorrhage” "F. Baganha, M.R. De Vries, Erna Peters, Knut Pettersson and P.H.A. Quax Rembrandt Symposium Green 10.5281/zenodo.1489038 10.5281/zenodo.1489038 55 " “Humanized IgG monoclonal anti-phosphorylcholine reduces vein graft failure” Baganha F. , M.R. De Vries, Erna Peters, Knut Pettersson and P.H.A. Quax AIO research meeting Green 10.5281/zenodo.1489028 10.5281/zenodo.1489028 56 Drug discovery and Computation Biology "Cristofori V. PechaKucha Night Green 10.5281/zenodo.1486103 10.5281/zenodo.1486103 57 Dysfunctional endothelial cells in patients with chronic thromboembolic pulmonary hypertension Valerie smolders 2 Reunión de Investigación en Hipertensión Pulmonar. No 10.5281/zenodo.1557576 10.5281/zenodo.1557576 58 Blockade of vascular endothelial growth factor receptor 2 inhibits intraplaque haemorrhage by normalization of plaque neovessels M. R. de Vries, L. Parma, H. A. B. Peters, A. Schepers, J. F. Hamming, J. W. Jukema, M. J. T. H. Goumans, L. Guo, A. V. Finn, R. Virmani, C. K. Ozaki, P. H. A. Quax Journal of Internal Medicine Green 10.1111/joim.12821 59 Pharmacokinetic drug interactions of the non-vitamin K antagonist oral anticoagulants (NOACs) Paolo Gelosa, Laura Castiglioni, Marco Tenconi, Ludovico Baldessin, Giorgio Racagni, Alberto Corsini, Stefano Bellosta Pharmacological Research Green 10.1016/j.phrs.2018.07.016 60 Proprotein Convertase Subtilisin-Kexin type-9 (PCSK9) and triglyceride-rich lipoprotein metabolism: Facts and gaps Andrea Baragetti, Daniela Grejtakova, Manuela Casula, Elena Olmastroni, Gloria Saccani Jotti, Giuseppe Danilo Norata, Alberico L. Catapano, Stefano Bellosta Pharmacological Research Green doi: 10.1016/j.phrs.2018.01.025 61 Adenosine-to-Inosine Editing of MicroRNA-487b Alters Target Gene Selection After Ischemia and Promotes Neovascularization Reginald V.C.T. van der Kwast, Eva van Ingen, Laura Parma, Hendrika A.B. Peters, Paul H.A. Quax, A. Yaël Nossent Circulation Research Green 10.1161/circresaha.117.312345 62 Metabolic Alterations in Cardiopulmonary Vascular Dysfunction Valérie Françoise Smolders, Erika Zodda, Paul H. A. Quax, Marina Carini, Joan Albert Barberà, Timothy M. Thomson, Olga Tura-Ceide, Marta Cascante Frontiers in Molecular Biosciences Green 10.3389/fmolb.2018.00120 63 Differentially Expressed Proteins in Primary Endothelial Cells Derived From Patients With Acute Myocardial Infarction Sarath Babu Nukala, Luca Regazzoni, Giancarlo Aldini, Erika Zodda, Olga Tura-Ceide, Nicholas L. Mills, Marta Cascante, Marina Carini, Alfonsina D’Amato Hypertension Green 10.1161/hypertensionaha.119.13472 64 Tuning PFKFB3 Bisphosphatase Activity Through Allosteric Interference Helena Macut, Xiao Hu, Delia Tarantino, Ettore Gilardoni, Francesca Clerici, Luca Regazzoni, Alessandro Contini, Sara Pellegrino, Maria Luisa Gelmi Scientific Reports Green 10.1038/s41598-019-56708-0 65 PFKFB3 gene deletion in endothelial cells inhibits intraplaque angiogenesis and lesion formation in a murine model of venous bypass grafting Perrotta P, de Vries MR, Peeters B, Guns P-J, De Meyer GRY, Quax PHA, Martinet W. Angiogenesis Gold 10.1007/s10456-021-09816-3 66 The PFKFB3 inhibitor AZ67 inhibits angiogenesis independently of glycolysis inhibition Emini Veseli B, Van Wielendaele P, Delibegovic M, Martinet W, De Meyer GRY Int J Mol Sci. Gold 10.3390/ijms22115970 67 Small molecule 3PO inhibits glycolysis but does not bind to 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase-3 (PFKFB3) Emini Veseli B, Perrotta P, Van Wielendaele P, Lambeir A-M, Abdali A, Bellosta S, Monaco G, Bultynck G, Martinet W, De Meyer GRY FEBS Lett. Gold 10.1002/1873-3468.13878 68 Three-dimensional imaging of intraplaque neovascularization in a mouse model of advanced atherosclerosis Perrotta P, Pintelon I, De Vries MR, Quax PHA, Timmermans J-P, De Meyer GRY, Martinet W. J Vasc Res. Green 10.1159/000508449 69 Partial inhibition of glycolysis reduces atherogenesis independent of intraplaque neovascularization in mice Perrotta P, Van der Veken B, Van der Veken P, Pintelon I, Adrianssens E, Timmerman V, De Meyer GRY, Martinet W. Arterioscler Thromb Vasc Biol. Gold 10.1161/atvbaha.119.313692 70 Derivation and characterisation of endothelial cells from patients with chronic thromboembolic pulmonary hypertension Olga Tura-Ceide, Valérie F.E.D. Smolders, Núria Aventin, Constanza Morén, Mariona Guitart-Mampel, Isabel Blanco, Lucilla Piccari, Jeisson Osorio, Cristina Rodríguez, Montserrat Rigol, Núria Solanes, Andrea Malandrino, Kondababu Kurakula, Marie Jose Goumans, Paul H.A. Quax, Victor I. Peinado, Manuel Castellà, Joan Albert Barberà Sci Rep Gold 10.1038/s41598-021-98320-1 71 Metabolic profile in endothelial cells of chronic thromboembolic pulmonary hypertension and pulmonary arterial hypertension V.F.E.D. Smolders Rodríguez C, I. Blanco, R. Szulcek, Wim Timens, L. Piccari, Y. Roger, X. Hu, Constanza Morén, C. Bonjoch, L. Sebastián, M. Castellà, J. Osorio, V. I. Peinado, Harm Jan Bogaard, P. H. A. Quax, M. Cascante, J.A. Barberà, O. Tura-Ceide Sci Rep Gold 10.21203/rs.3.rs-1008061/v1 72 The Inflammatory Profile of CTEPH Derived Endothelial Cells is a Possible Driver of Disease Progression Valérie F.E.D. Smolders, Kirsten Lodder, Cristina Rodriguez, Olga Tura-Ceide, Joan Albert Barberà, J. Wouter Jukema, Paul H.A. Quax, Marie José T.H. Goumans, Kondababu Kurakula Cells Gold 10.3390/cells10040737 73 Protein network analyses of pulmonary endothelial cells in chronic thromboembolic pulmonary hypertension Sarath Babu Nukala, Olga Tura-Ceide, Giancarlo Aldini, Valérie Smolders, Isabel Blanco, Victor I. Peinado, Manuel Castellà, Joan Albert Barberà, Alessandra Altomare, Giovanna Baron, Marina Carini, Marta Cascante and Alfonsina D’Amato Sci Rep Gold 10.1038/s41598-021-85004-z 74 Decreased glycolysis as metabolic fingerprint of endothelial cells in chronic thromboembolic pulmonary hypertensio Valérie F. Smolders, Cristina Rodríguez, Isabel Blanco, Jeisson Osorio, Lucilla Piccari, Cristina Bonjoch, Paul H.A. Quax, Victor I. Peinado, Manel Castellà, Joan Albert Barberà, Marta Cascante, Olga Tura-Ceide American Journal of Respiratory Cell and Molecular Biology Gold 10.1165/rcmb.2019-0409le 75 [18F]ZCDD083: a PFKFB3-targeted PET tracer for atherosclerotic plaque imaging Carlo De Dominicis, Paola Perrotta, Sergio Dall’Angelo, Leonie Wyffels, Steven Staelens,* Guido R. Y. De Meyer, Matteo Zanda ACS Medicinal Chemistry Letters Green 10.1021/acsmedchemlett.9b00677 76 Endothelial Dysfunction in Pulmonary Hypertension: Cause or Consequence? Kondababu Kurakula, Valérie F.E.D Smolders, Olga Tura-Ceide, J. Wouter Jukema, Paul H. A. Quax, Marie-José Goumans Biomedicines Gold 10.3390/biomedicines9010057 77 In vitro angiogenesis inhibition with selective compounds targeting the key glycolytic enzyme PFKFB3 Abdali A, Baci D, Damiani I, Belloni F, De Dominicis C, Gelmi ML, Corsini A, Bellosta S. Pharmacol Res Green 10.1016/j.phrs.2021.105592 78 Atorvastatin pleiotropically decreases intraplaque angiogenesis and intraplaque haemorrhage by inhibiting ANGPT2 release and VE-Cadherin internalization Fabiana Baganha; Fabiana Baganha; Rob C.M. de Jong; Erna Peters; Wietske Voorham; J. Wouter Jukema; Mirela Delibegovic; Margreet R. de Vries; Paul H.A. Quax Angiogenesis Gold 10.1007/s10456-021-09767-9 http://hdl.handle.net/1887/3214288 79 Prolonged Hyperoxygenation Treatment Improves Vein Graft Patency and Decreases Macrophage Content in Atherosclerotic Lesions in ApoE3*Leiden Mice. Parma, Laura; Peters, Hendrika A. B.; Baganha, Fabiana; Sluimer, Judith C.; de Vries, Margreet R.; Quax, Paul H.A. Cells, 9(2):336. Multidisciplinary Digital Publishing Institute (MDPI) Gold 10.3390/cells9020336 https://dx.doi.org/10.3390/cells9020336 80 Rescoring Virtual Screening Results with the MM-PBSA Methods: Beware of Internal Dielectric Constants Hu, Xiao; Contini, Alessandro JOURNAL OF CHEMICAL INFORMATION AND MODELING Green 10.1021/acs.jcim.9b00095 http://hdl.handle.net/2434/651769 81 Mass Spectrometry-based Label-free Quantitative Proteomics To Study the Effect of 3PO Drug at Cellular Level Nukala, S.B.; Baron, G.; Aldini, G.; Carini, M.; D' Amato, A. ACS Med chem lett Gold 10.1021/acsmedchemlett.8b00593 https://dx.doi.org/10.1021/acsmedchemlett.8b00593 82 The Role of Immunomodulation in Vein Graft Remodeling and Failure. Fabiana Baganha; Fabiana Baganha; Alwin de Jong; J. Wouter Jukema; Paul H.A. Quax; Margreet R. de Vries Journal of Cardiovascular Translational Research Gold 10.1007/s12265-020-10001-y http://europepmc.org/articles/PMC7892738 83 Assessment of Microvessel Permeability in Murine Atherosclerotic Vein Grafts Using Two-Photon Intravital Microscopy Baganha F, Ritsma L, Quax PHA, de Vries MR Int J Mol Sci. 2020 Gold 10.3390/ijms21239244 84 Adenosine-to-Inosine Editing of Vasoactive MicroRNAs Alters Their Targetome and Function in Ischemia van der Kwast RVCT, Parma L, van der Bent ML, van Ingen E, Baganha F, Peters HAB, Goossens EAC, Simons KH, Palmen M, de Vries MR, Quax PHA, Nossent AY Mol Ther Nucleic Acids Gold 10.1016/j.omtn.2020.07.020 85 bFGF blockade reduces intraplaque angiogenesis and macrophage infiltration in atherosclerotic vein graft lesions in ApoE3*Leiden mice. Parma L, Peters HAB, Sluiter TJ, Simons KH, Lazzari P, de Vries MR, Quax PHA Sci Rep. Gold 10.1038/s41598-020-72992-7 86 Bis(maltolato)oxovanadium(IV) Induces Angiogenesis via Phosphorylation of VEGFR2. Parma L, Peters HAB, Johansson ME, Gutiérrez S, Meijerink H, de Kimpe S, de Vries MR, Quax PHA Int J Mol Sci. Gold 10.3390/ijms21134643 87 Inhibition of 14q32 microRNA miR-495 reduces lesion formation, intimal hyperplasia and plasma cholesterol levels in experimental restenosis. Welten SMJ, de Jong RCM, Wezel A, de Vries MR, Boonstra MC, Parma L, Jukema JW, van der Sluis TC, Arens R, Bot I, Agrawal S, Quax PHA, Nossent AY Atherosclerosis Gold 10.1016/j.atherosclerosis.2017.04.011
