[18F]ZCDD083: A PFKFB3-Targeted PET Tracer for Atherosclerotic
Plaque Imaging
PFKFB3, a glycolysis-related enzyme upregulated in inflammatory conditions and angiogenesis, is an emerging target for diagnosis andtherapy of atherosclerosis. The fluorinated phenoxindazole [18F]ZCDD083 was synthesized, radiolabeled in 17 ± 5% radiochemical yield and >99%radiochemical...